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Re: Nierenberg - Clonidine for bipolar depression? » JohnX

Posted by Mitch on October 23, 2001, at 12:43:15

In reply to Re: Nierenberg - Clonidine for bipolar depression?, posted by JohnX on October 22, 2001, at 23:25:53

> Scott,
>
> One thing is curious.
> Bupropion is thought to inhibit firing of neurons
> in the primary area affected by the alpha-2 receptors.
> Remeron's alpha-2 antagonism increases firing.
>
> -john


John, thanks for that info! That is VERY peculiar, because I get God-awful irritability on any meds that antagonize alpha-2 receptors. Strangely, when I am on Wellbutrin I am a little edgy and nauseous, BUT I never noticed any irritability or hypomania...

Mitch


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URL: http://www.dr-bob.org/babble/20011015/msgs/82074.html