Posted by petters on October 20, 2001, at 13:46:26
In reply to Nierenberg - Clonidine for bipolar depression?, posted by SLS on October 19, 2001, at 16:44:56
> Hi Doctor.
>
> I suffer from TRD chronic bipolar depression. Several medications make me feel significantly worse, including mirtazepine and idazoxan. I recently attempted to add mirtazepine to an ongoing trial of venlafaxine. Within 12 hours of my first 7.5mg dose, my condition began to deteriorate in a manner similar to those previous. Might this suggest trying a drug that exerts an opposite effect at NE alpha-2 receptors (e.g. clonidine) ?
>
> I’m upset because the two drug combinations using venlafaxine that my doctor thought would have the best chances of working for me involve using drugs to which I have previously experienced negative reactions – bupropion and mirtazepine.
>
> Thanks.
>
>
> - ScottHi Scott...
About Clonidine. I know some folks who find it usefull in social phobia. In bipolar depression...I have never heard anything about it-Sorry.
By the way What about the Citalopram add to your current regim? Ziprasidone didn´t do so mutch, for you state, it I remeber it right.
Have you ever tried yohimbin?
What about Amantadin? I know one doc who use it in TRD as an add on. Since it enhance the efect on the other meds.Sincerely
Petters
poster:petters
thread:81697
URL: http://www.dr-bob.org/babble/20011015/msgs/81795.html