Psycho-Babble Medication Thread 52219

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Has anyone tried modafinil (Provigil)?

Posted by PhoenixGirl on January 22, 2001, at 10:54:39

I am interested in trying this drug. I want it to replace my desipramine or allow me to reduce desipramine because of desipramine's sexual side effects. Please tell me about your experience with modafinil/Provigil, regarding effectiveness and side effects.

 

Re: Has anyone tried modafinil (Provigil)?

Posted by JohnL on January 23, 2001, at 2:36:24

In reply to Has anyone tried modafinil (Provigil)?, posted by PhoenixGirl on January 22, 2001, at 10:54:39

> I am interested in trying this drug. I want it to replace my desipramine or allow me to reduce desipramine because of desipramine's sexual side effects. Please tell me about your experience with modafinil/Provigil, regarding effectiveness and side effects.

Hi,
I have tried Modafinil. I thought it was just awful. I do recall a couple people here that tried it and liked it. Not me though.

The first day was kind of nice. Lots of energy, quick thinking, good mood. But the second day was different, more sluggish, and without the nice bounce. The third day I was slowing even more. I would get physically exhausted very easy, and yet my mind was working fast. I became uninterested in doing anything, and yet if I forced myself to do something I could get totally engrossed in it until it was done. And then I would realize how totally tired and exhausted I felt. And there was this strange craving for another dose, almost like an addiction. I became so lethargic, cloudy minded, and no appetite. I thought maybe I had a touch of the flu. It felt like that. But it wasn't a flu.

I just really didn't like Modafinil at all. I highly prefer the ancestor from which it was invented. Adrafinil. Not only is Adrafinil far better--in my opinion only--but it is dirt cheap as well. Modafinil is very expensive.
John

 

Re: Has anyone tried modafinil (Provigil)?

Posted by Lee on January 23, 2001, at 6:32:52

In reply to Has anyone tried modafinil (Provigil)?, posted by PhoenixGirl on January 22, 2001, at 10:54:39

> I am interested in trying this drug. I want it to replace my desipramine or allow me to reduce desipramine because of desipramine's sexual side effects. Please tell me about your experience with modafinil/Provigil, regarding effectiveness and side effects.

I began provigil augmentation of Effexor to treat depression about six weeks ago. The first two days - 200 mg. each morning - were remarkable. I felt a calm and contentment throughout the day.

Six weeks later and I am taking 400 mg. each morning (sometimes 500 mg.). The mood brightening effect fades around noon. The rest of the day I is odd: I experience depression but remain energized from the provigil. Mind you, I would rather be depressed and energized than depressed and fatigued (which is how I have felt these past two decades) but the combination can seem disconcerting. So far, I have experienced no side effects.

I suggest you trial provigil with an AD. (I don't know how it combines with the range of ADs however.) It can bring relief.

I hope this personal information is helpful.



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