Posted by Sunkistcat79 on January 2, 2009, at 11:22:26
In reply to Kappa opioid receptors and dopamine, posted by undopaminergic on May 22, 2008, at 10:24:20
In my present state (severe severe depression) my ability to comprehend and discuss at the level of these posts is diminished, but I still hope I am welcome to be involved. I am educated (BA in early childhood education) so the science realm for me generally involves observing and drawing pinecones with crayons.
However, I was once able to research, retain and understand this subject. Here's how:
Coming from a place where my only addictions involved food and people, I took oxycodone after a car accident. This happened right in the middle of a SEVERE depression. And, without any chance of any placebo effect (at first refused to take the oxycodone because i didnt know what it was), my depression INSTANTLY vanished.
Ok, you're thinking...DUH!
Well, it wasn't a "fun-party" experience. I felt alert and calm, happy- NOT in manic way, as i mentioned before, able to read and retain difficult academic studies on neurotransmitters, kappa receptors, thebaine, etc.
I was able to do the WORK on my self I had been trying to do for YEARS. My doctor understood this phenomenon and put me on Burprnorphine (subutex). Those vile bitter pills were the most delicious, welcomed taste I have EVER known.
My one side effect involved the end of my digestive track but every time I was reminded of this typically unpleasant situation, I smiled - knowing that I was happy.I made plans to get back together and then move in with my then ex-boyfriend. By the time I moved in, I spent the first night curled up in a ball in the corner, crying hysterically - his sweet words and hugs just made me sadder. None of it made sense - I had wanted to live with him for over a year and now I was...and I just wanted to die. Something wasn't working.
When I took my fist opioid, I was taking lexapro and wellbutrin. After a month, I weaned carefully off of them and that's when problems started (that's about when I moved in). I was sure then that somehow the 3 or 2 drugs interacted and I needed to continue with all of them. However, when I got back on the other two, there was NO change.
I KNOW how I felt on the opioids is how people are supposed to feel. I got upset by things still, but I was able to CONTRTOL it. That is something I have never been able to do.
I have always known and been told that I am very physically sensitive. Doctor presented this to my mother at my Apgar test. - so decreased endorphins would make sense, yeah?
I had a miracle before.
I NEED AND DESERVE ANOTHER ONE. very very very soon.
Please feel free to read my general post (posted within the hour from this one) on the newbie board.Please...ASK ME ANY QUESTIONS.
Provide me with any information - I'll try to find a way to read it.
Refer me to doctors who will study me (I'll submit to anything short of a spinal tap.Thank you for reading and responding.
poster:Sunkistcat79
thread:830482
URL: http://www.dr-bob.org/babble/neuro/20080706/msgs/871914.html