Posted by undopaminergic on December 17, 2019, at 11:06:25
In reply to Re: Dextromethorphan/Bupropion for MDD soon....., posted by PeterMartin on December 17, 2019, at 3:05:50
> Dextromethorphan works the NMDA receptor so it's novel in that regard. There are other drugs (new) in trial that work by touching on NMDA.
>Dextromethorphan (DXM) is also a serotonin reuptake inhibitor. I noticed this myself. It is probably a sigma-receptor agonist too, but I'm not 100% sure about that.
It does work on NMDA. So does memantine, which was so "good" it made me manic. I was having so much fun just from YouTube. Alas, I got impulsive and took an overdose of a few grams, so I'm probably the world record-holder in the category of highest dose of memantine taken.
I'm not sure whether I was trying to kill myself... I guess I was a bit confused.
-undopaminergic
poster:undopaminergic
thread:1107271
URL: http://www.dr-bob.org/babble/20191019/msgs/1107281.html