Posted by PeterMartin on December 16, 2019, at 14:18:39
A combo drug of Dextromethorphan & Bupropion has done well in trials. It's essentially Robitussin + Wellbutrin. I used to take Robitussin in excess and it definitely helped my mood a lot. I found taking it w/ Lamictal worked well to leave just the mood enhancing effects (and eliminate the "tripping" part).
Anyway, NDA next year. Sadly I'm sure they'll charge through the roof for it even though it's 2 chemicals that have had cheap generic versions available for ages. I think Nudexda (alzheimers) was a similar repurposing of Dextromethorphan that ran $500+ a month.
Info on it's trial success/NDA next year:
poster:PeterMartin
thread:1107271
URL: http://www.dr-bob.org/babble/20191019/msgs/1107271.html