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Re: Need thoughts as to where to go next- longer post » SLS

Posted by seekinginformation on November 2, 2014, at 10:32:26

In reply to Re: Need thoughts as to where to go next- longer post » seekinginformation, posted by SLS on November 2, 2014, at 8:03:06

Hi Scott,
One other thing I forgot to mention... the Clomipramine. My Mom has OCD, as does my twin brother. They both took it at one point.

My mom seemed to be able to handle it, but the side effects eventually drove her off of it and back to an SSRI. She gained weight and was generally "a zombie" for lack of a better word, even at a lower dose. She really checked out on life while she was on it.

My twin tried it, and it caused intense anxiety and racing heart to the point that he was told to stop taking it.

Mental illness runs in my immediate family and extended family, particularly OCD and GAD.

> How do you respond to fluvoxamine (Luvox)?
>
> Fluvoxamine, along with its serotonergic properties, is a sigma-1 receptor agonist, which may act to mitigate the akathisia produced by neuroleptic antipsychotics. It will certainly be less apt to produce akathisia than other SSRIs. Sertraline (Zoloft) is probably the worst SSRI with respect to producing akathisia. This is not completely unexpectied, though. Sertraline is the SSRI that is most potent as a sigma-1 receptor antagonist.
>
> How do you respond to clomipramine (Anafranil)?
>
>
> - Scott


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poster:seekinginformation thread:1073091
URL: http://www.dr-bob.org/babble/20141017/msgs/1073110.html