Posted by bleauberry on September 24, 2010, at 17:32:22
In reply to Re: Do not do it! » Sigismund, posted by John45 on September 23, 2010, at 7:59:33
It is my belief that the reason various approaches of opioid meds do wonders for depression is because of this....
Toxins have a high affinity for opioid receptors. That disrupts not only our endorphins, but indirectly serotonin and dopamine as well. Toxins I am talking about include such things as aluminum (everywhere), cadmium(cigarettes), lead(everywhere), mercury(everywhere), and the poop, pee, and chemicals of infectious pathogens that we never suspected we had but we do (much more epidemic than anyone suspects).
Meds like vicadin, buprenorphine, or ldn, do something....they competitively displace whatever toxins are residing (clogging) the opioid receptors. That's why some people experience profound antidepressant effect from opioid meds, but not the euphoria or dysphoria experienced by a normal healthy person. The med is simply competitively displacing the toxin and allowing the receptor to do what it was designed to do.
Obviously this only applies to an unknown subset of depressive patients, since not everyone is suffering from an unknown toxic load. And not everyone will have a good outcome on the opioid journey.
If nothing else, I believe the use of these kinds of meds as quick challenge trials is a powerful diagnostic tool. It can help steer someone stuck in the failed psych office to someone who knows about infections and detox. The reaction to a challenge trial of opioid meds supplies a lot of useful detective information. Euprhoria, dysphoria, remission...whatever happens, it tells a story and gives direction in treatment.
poster:bleauberry
thread:963457
URL: http://www.dr-bob.org/babble/20100917/msgs/963631.html