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Re: Fluoxetine = 5-HT2c Potent antagonist ? ..confused » Marty

Posted by SLS on August 6, 2008, at 5:04:00

In reply to Fluoxetine = 5-HT2c Potent antagonist ? ..confused, posted by Marty on August 5, 2008, at 19:39:36

Hi Marty.

> If Prozac is one of the most potent 5-HT2C and end up being one of the worst at the sexual level then ... there's way more to the story than just 5-HT2C .. Any thoughts ?

None.

:-)

However, that was a great bit of snooping, Marty. Thanks.

Hmm. Perhaps at therapeutically relevant dosages, 5-HT kicks off the Prozac and replaces it on the 5-HT2c receptor?

How much do you suppose activating 5-HT2a receptors might disrupt sexual function? If it does, then that would be another avenue that by which a biphasic effect might occur.

Stahl is really something.


- Scott

 

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