Posted by dr. dave on October 31, 2002, at 8:26:26
In reply to Re: Citalopram pharmacology » dr. dave, posted by SLS on October 30, 2002, at 7:26:31
Dear Scott,
> Do you feel you know enough about the brain, physiology, organic chemistry, and the pharmacology of these two drugs to state anything about getting down to science? I admit that I don't (not such a revelation). I just like doing thought experiments - you know - theory. My theories are constructed with great care but with insufficient knowledge for them to be worth a damn.I'm sorry if anything I've said seems arrogant. The main point I've been trying to make on this board is that claims are being made on very weak evidence about this drug, and there is no clear reason why, pharmacologically, the claims would be true - by which I mean there's no plausible mechanism of action (for any superiority over citalopram) that's been substantiated at all.
I feel qualified to comment on the science as it's what I've been educated in for many years, and it's my job to have an understanding of it - but I'm only commenting, which is not to say I don't get things wrong sometimes.
I couldn't agree more that what matters is what happens in real life, whatever the theories. Obviously Lexapro helps a lot of people and I'm not sure I have ever suggested otherwise. Whether it turns out to be significantly different from Celexa time will tell.
David
poster:dr. dave
thread:109458
URL: http://www.dr-bob.org/babble/20021025/msgs/125918.html