Posted by Patson on September 2, 2002, at 20:46:28
In reply to Re: Raines et al, posted by dr dave on September 1, 2002, at 8:23:59
I have to admit I'm a little confused. Maybe I don't understand english all that well....
The investigators observed continued improvement in subjects with further reductions in the MADRS and CGI-S scores. ****The incidence of adverse events declined during escitalopram treatment versus short-term treatment. ****There were no clinically significant mean changes in vital signs, electrocardiogram (ECG), or laboratory values observed during continued escitalopram treatment, regardless of previous treatment. Researchers observed no new clinically significant adverse events in patients switching from citalopram to escitalopram treatment.
"In patients switched from citalopram to escitalopram, there are no safety concerns, and depressive symptoms continue to improve." the researchers concluded.
Hardly sounds like a negative...
> You can find a report by going to http://www.docguide.com and searching for 'escitalopram'. There is a news report dated 08/29/02 on the switching study. If there were any difference between citalopram and escitalopram the side-effects would have decreased and this would have been a major finding. It is noticeable by its absence.
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> > "Indeed new research presented this week (Raines et al) looking at people switching from citalopram to escitalopram did not show any significant reduction in side-effects."
> >
> > That sounds important. Got a link? Or, can you copy and post?
> >
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poster:Patson
thread:109458
URL: http://www.dr-bob.org/babble/20020829/msgs/118605.html