Posted by JaneB on September 2, 2002, at 18:17:30
In reply to Re: poop-out, posted by pharmrep on September 2, 2002, at 17:28:16
> Cycling or "poop-out" takes a long time to evaluate. You are right about being on higher mg's to be affected...I have heard that. So if you are on 80+mg of Celexa (after titrating up from 20-40-60 over time) then you might get poop-out eventually...but not necessarily. If you have been on the same mg of something for a long time (low or high mg) then cycling should be less likely to occur. It is not an exact science, so nobody is sure on how or why it happens. Some people have taken prozac for 15 years, no probs...others needed to titrate up 10mg every few years or so, and now take 100+mg of prozac...anyway, you see the picture...hope this helps.
"Cycling" and "poop out" are not the same at all. If an AD prescribed for depression "poops out" there are no good days. Just old depression and a dr. will up the dosage as you say. However, if there is "cycling" it is a spectrum of bipolar illness and can be induced by AD's. "Cycling" in this sense means highs and lows. Therefore, physicians should not prescribe antidepressants without being aware and following up a patient to watch for and educate patient about potential cycling caused by AD's. I think that some people who see all the ads of people laughing and feeling great may end up asking for an AD and subsequently find themselves worse off because of this potential for cycling and ignorance of the need for a mood stabilizer. (IMO). But you are not a patient or physician and have probably never found it necessary to research something of this nature. If I am wrong I welcome correction re. definition of "cycling", etc.
You are right--"poop out" takes a long time to evaluate. But "cycling" can happen right away with introduction of AD's and increased dosage for someone with bipolar tendencies. That is why I would change to Lexapro cautiously because it seems that I would be receiving more of the active antidepressant. Does this make sense?
Thanks,
JaneB
poster:JaneB
thread:109458
URL: http://www.dr-bob.org/babble/20020829/msgs/118593.html