Psycho-Babble Alternative Thread 1056601

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Glutathione Supplement opposed to NAC

Posted by Lamdage22 on December 20, 2013, at 2:29:09

http://thorne.com/Products/Amino_Acids_Proteins/Amino_Acids/prd~SA540.jsp

Anyone?

I have some trouble with NAC initially. At first it makes me feel great, then after couple days i have suicide thoughts again.

 

Re: Glutathione Supplement opposed to NAC

Posted by Tomatheus on December 20, 2013, at 16:09:07

In reply to Glutathione Supplement opposed to NAC, posted by Lamdage22 on December 20, 2013, at 2:29:09

Lamdage22,

I'm not sure how a glutathione supplement would compare with N-acetylcysteine for suicidal thinking. I noticed an increase in agitation when I took NAC before the onset of my psychosis, but I'm not sure how it would affect me now. I also tried a sublingual version of glutathione not too long ago with my Abilify, and I think I noticed some benefits from it for about two weeks (as far as energy, concentration, and hypersomnia were concerned) before it ended up becoming seemingly ineffective.

Having said what I've said, I'm not aware of any studies that have been done on the effectiveness of glutathione supplementation for affective disturbances. That's not to say that it might not be worth trying.

Tomatheus

 

Re: Glutathione Supplement opposed to NAC

Posted by Lamdage22 on December 21, 2013, at 1:33:53

In reply to Re: Glutathione Supplement opposed to NAC, posted by Tomatheus on December 20, 2013, at 16:09:07

> Lamdage22,
>
> I'm not sure how a glutathione supplement would compare with N-acetylcysteine for suicidal thinking. I noticed an increase in agitation when I took NAC before the onset of my psychosis, but I'm not sure how it would affect me now. I also tried a sublingual version of glutathione not too long ago with my Abilify, and I think I noticed some benefits from it for about two weeks (as far as energy, concentration, and hypersomnia were concerned) before it ended up becoming seemingly ineffective.
>
> Having said what I've said, I'm not aware of any studies that have been done on the effectiveness of glutathione supplementation for affective disturbances. That's not to say that it might not be worth trying.
>
> Tomatheus

Well i know that NAC derives part of its effect from increased Gluthatione.

 

Re: Glutathione Supplement opposed to NAC » Lamdage22

Posted by Tomatheus on December 21, 2013, at 1:56:11

In reply to Re: Glutathione Supplement opposed to NAC, posted by Lamdage22 on December 21, 2013, at 1:33:53

> Well i know that NAC derives part of its effect from increased Gluthatione.

Yes, but the two could conceivably be different in terms of effectiveness. I know that there's some thinking that glutathione might not cross the blood-brain barrier, which might limit its usefulness as a supplement. I think that NAC does cross the blood-brain barrier, and I sometimes wonder about the extent to which the therapeutic benefits of NAC may be due to its acetyl group (I'm thinking that it could be used to make the neurotransmitter acetylcholine and that that may be beneficial for some individuals).

Tomatheus

 

Re: Glutathione Supplement opposed to NAC

Posted by Lamdage22 on December 21, 2013, at 6:16:16

In reply to Re: Glutathione Supplement opposed to NAC » Lamdage22, posted by Tomatheus on December 21, 2013, at 1:56:11

Oh ok. I plan to maybe up the NAC to 1200mg. But first i want the EPA effect to stabilize.

But only if it really makes me feel better. Short term, first 4 days i feel "great" at least compared to how i felt before. Then the suicide thoughts creeped back in and were maybe a bit more intense thatn without it. But i wonder what it would do for me long term.

> > Well i know that NAC derives part of its effect from increased Gluthatione.
>
> Yes, but the two could conceivably be different in terms of effectiveness. I know that there's some thinking that glutathione might not cross the blood-brain barrier, which might limit its usefulness as a supplement. I think that NAC does cross the blood-brain barrier, and I sometimes wonder about the extent to which the therapeutic benefits of NAC may be due to its acetyl group (I'm thinking that it could be used to make the neurotransmitter acetylcholine and that that may be beneficial for some individuals).
>
> Tomatheus

 

Re: Glutathione Supplement opposed to NAC » Lamdage22

Posted by Tomatheus on December 21, 2013, at 12:41:06

In reply to Re: Glutathione Supplement opposed to NAC, posted by Lamdage22 on December 21, 2013, at 6:16:16

Lamdage22,

I wish you luck in getting the benefits that you're looking to get from the EPA. I can relate, unfortunately, to getting short-lived responses from supplements, and I hope that your strategy will end up being beneficial for you in the long run.

Tomatheus


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