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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by valene on March 22, 2007, at 16:01:44
Medscape article I found interesting:
Bupropion normalizes cognitive performance in patients with depression :
http://www.medscape.com/viewarticle/550429hypothesis: "cognitive benefit may occur relative to an ADs norepinephrine activity, while lack of benefit may relate to its serotonergic activity. Bupropion is associated with normal function. Venalfaxine performs less well than bupropion but better than the SSRI's. This is consistent with the principle that enhanced norepinephrine metabolism is associated with better cognitive performance of a variety of neurocognitive tasks."
(This study was supported by a grant to the investigators from GlaxoSmithKline)
Posted by TheMeanReds on March 22, 2007, at 17:38:38
In reply to Bupropion Normalizes Cognitive Performance in depr, posted by valene on March 22, 2007, at 16:01:44
I mentioned Bupropion to my doc after researching it. He said it was very weak, almost the equivalant of taking a benedryl. Never got to try it. Maybe in the future though.
Posted by Phillipa on March 22, 2007, at 19:49:19
In reply to Bupropion Normalizes Cognitive Performance in depr, posted by valene on March 22, 2007, at 16:01:44
Valene so what have you decided? Love Phillipa
Posted by linkadge on March 22, 2007, at 19:52:40
In reply to Re: Bupropion Normalizes Cognitive Performance in depr » valene, posted by Phillipa on March 22, 2007, at 19:49:19
(This study was supported by a grant to the investigators from GlaxoSmithKline)
Linkadge
Posted by Joe Bloe on March 22, 2007, at 20:28:30
In reply to Re: Bupropion Normalizes Cognitive Performance in depr, posted by TheMeanReds on March 22, 2007, at 17:38:38
> I mentioned Bupropion to my doc after researching it. He said it was very weak, almost the equivalant of taking a benedryl. Never got to try it. Maybe in the future though.
Like Benadryl? Not at all! I think the subjective feel of Bupropion is actually quite opposite from Benadryl! Benadryl is used in sleep medicine, bupropion can be highly activating. I would not classify Bupropion as weak either. I found it to have strong antidepressant qualities, but it made me kind of hypomanic and angry.
Posted by Phillipa on March 22, 2007, at 21:40:17
In reply to Re: Bupropion Normalizes Cognitive Performance in, posted by Joe Bloe on March 22, 2007, at 20:28:30
Same here put me in the hospital for a week as the pdoc thought I was going hypomanic. Very activating. Love Phillipa
Posted by TheMeanReds on March 23, 2007, at 12:05:22
In reply to Re: Bupropion Normalizes Cognitive Performance in » Joe Bloe, posted by Phillipa on March 22, 2007, at 21:40:17
Oops, I got Brupropion terribly mixed up with Buspirone. My doctor said Buspirone was like Benadryl, not the Bupropion.
I actually tried Wellbutrin (Brupropion), and yes it was extremely activating for me. And actually was too activating for my anxiety. I had insisted that I try it, since I read tons of success stories. I was only on it for 2 doses, and I had a panic attack. I'm sensitive though to the activating drugs.
Sensitive enough to need to have 2mg/day Xanax, with 100mg/day Lamictal (which is an activator for me).
Posted by valene on March 23, 2007, at 12:56:16
In reply to Re: Bupropion Normalizes Cognitive Performance in depr » valene, posted by Phillipa on March 22, 2007, at 19:49:19
> Valene so what have you decided? Love Phillipa
Phillipa,
I'm sticking with the 37.5mg. until I talk further with my pdoc. Don't know if I will be able to tolerate the higher doses I would need to help depression. May just use cognitive therapy and always prayer!PS Im staying at my Mom's who had cataract surgery and can't see out of the other eye due to retinal problem. Will email when I get home....
Love,
Val
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