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Bupropion Normalizes Cognitive Performance in depr

Posted by valene on March 22, 2007, at 16:01:44

Medscape article I found interesting:

Bupropion normalizes cognitive performance in patients with depression :
http://www.medscape.com/viewarticle/550429

hypothesis: "cognitive benefit may occur relative to an ADs norepinephrine activity, while lack of benefit may relate to its serotonergic activity. Bupropion is associated with normal function. Venalfaxine performs less well than bupropion but better than the SSRI's. This is consistent with the principle that enhanced norepinephrine metabolism is associated with better cognitive performance of a variety of neurocognitive tasks."
(This study was supported by a grant to the investigators from GlaxoSmithKline)


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