![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by saturn on June 25, 2006, at 19:07:24
It seems that Provigil is actually *not* a central alpha 1 agonist, from what I gather, though much circulating data still says so.
Does anyone know if provigil has peripheral alpha 1 agonistic actions?
Is it safe to combine a beta blocker w/ Provigil to counter any excess peripheral stimulation if provigil is an alpha one agonist (or in any instance)?
I'm wondering if this would cause excess alpha 1 stimulation. My understanding is that beta receptors cause peripheral vasodilation whereas alpha causes constriction. Blocking beta without blocking alpha--or even further stimulating the receptor can lead to excessive vasoconstriction and resulting hypertension and possibly resulting heart problems, etc...
Any thoughts? Thanks. Peace. Saturn.
Posted by ed_uk on June 27, 2006, at 16:00:47
In reply to does provigil have peripheral alpha1 actions?, posted by saturn on June 25, 2006, at 19:07:24
Hi Saturn
>Does anyone know if provigil has peripheral alpha 1 agonistic actions?
AFAIK, it doesn't.
Regards
Ed
Posted by saturn on June 27, 2006, at 19:56:18
In reply to Re: does provigil have peripheral alpha1 actions? » saturn, posted by ed_uk on June 27, 2006, at 16:00:47
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.