Posted by qbsbrown on August 10, 2009, at 9:41:43
In reply to Re: Scott, new trend. Your theory? » qbsbrown, posted by SLS on August 10, 2009, at 6:53:49
> Although I try to stay away from theory and go with what works empirically, I am sure there are specific reasons for why you are experiencing these post-dose phenomena.
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> Tegretol potentiates GABA receptor stimulation and blocks sodium channels. With hyperexcitable glutamate neurons, you might get a combination of anxiety and dysphoria at the same time towards the end of the dosing period. Until the sodium channels become occupied again, the anxiety would persist during a time when increased GABA receptors occupancy produces the dysphoria. I am still mulling all of this over, so I am sure I've got it wrong.
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> Anyway, you can increase the dosage of Tegretol whenever you feel comfortable. It might prevent interdose loss of glutamate suppression and stop the rollercoaster ride.
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> I am glad that you are getting out more and functioning better.
>
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> - ScottWell, it seems that the dysphoria has rubbed off for the most part. I think it was more of a situational thing. Where I haven't been in many social situations, because they have been too difficult to tolerate, and just the pressure stemming from it.
I think perhaps that 4 doses might be more prudent. Is it ok to dose at 6am-10am-2pm-10pm? Or is that last space too much? I might find that if I dose at 10, that I won't need the 2pm so early. I begin to do my strange obsessional/compulsive quirks around 10am, and it seems to alieviate it w/ in 30 mins, so i'd like to do it then
I'm sure that you are more for advocating the ER version, but it just seems to act so much differently, I don't know why.
Regards,
Brian
poster:qbsbrown
thread:906673
URL: http://www.dr-bob.org/babble/wdrawl/20090801/msgs/911291.html