Posted by mav27 on September 3, 2008, at 8:57:34
Hi, i have a question about the way amisulpride works. I'll post the info from wiki that explains the part im interested in
" Its dosage ranges from 200 to 1200 mg/day. Lower doses (less than 50 mg) preferentially block D2 autoreceptors that control the synthesis and release of dopamine. This results in an increase in dopaminergic transmission. "
Anyway what i'm wondering is does this only happen at the low dose? When you increase the dose to the typical doses used for psychosis (over 200mg i believe) does the effects of the low dose stop and it just becomes like a typical receptor antagonist or do both actions occur ?
poster:mav27
thread:850048
URL: http://www.dr-bob.org/babble/neuro/20080706/msgs/850048.html