Posted by Carlton on March 17, 2008, at 13:13:52
I posted this in medications and only afterwards realized that it would be more appropriate to post under alternative -
First, I am aware that taking any supplements with Nardil is dangerous and can, ultimately, be fatal. For that matter, it is my understanding that having a glass of wine and cheese can be fatal for uses of phenelzine.With that said, I am aware that there have been studies which tested very low dosages of PEA with certain MAO inhibitors, who had been administered selegiline (L-deprenyl). I am not aware of any studies which combined PEA or DLPA as an adjunct treatment with Phenelzine for depression. I quote from one study, below, but the information regarding PEA with Phenelzine is sparse, to say the least.
Is there a difference between Nardil and selegiline (L-deprenyl)?
And, secondly, has anyone tried to supplement Phenelzine (nardil) with PEA or DLPA (DL-phenylalanine).
If so, what dosage of PEA or DLPA and Nardil?
What were the effects?
"Phenylethylamine (PEA), an endogenous neuroamine, increases attention and activity in animals and has been shown to relieve depression in 60% of depressed patients." See Sabelli H, Fink P, Fawcett J, et al. Sustained antidepressant effects of PEA replacement. J Neuropsychiatry
1996;8:16871"In depressed subjects treated with an MAOI, PEA markedly improves mood (because PEA is rapidly metabolized. PEA alone produces no noticeable effects). The addition of 10 to 30 mg/day of PEA to current treatment withamitriptyline plus phenelzine terminated the episode of depression in 2 of the 3 inpatients with MOD who had not achieved any significant recovery with tricyclic antidepressants, MAOI, or their combination. No significant side effects were noted. Patients noted a reduction of appetite, which had been increased by the antidepressants used." Sabelli H, Javaid J. Phenylethlyamine modulation of affect: therapeutic and diagnostic implications. J Neuropsychiatry Clin Neuroscience 1995;7:614
poster:Carlton
thread:818443
URL: http://www.dr-bob.org/babble/alter/20080110/msgs/818443.html