Posted by sregan on October 2, 2006, at 13:40:14
In reply to Re: Does anyone think SAMe works? » sregan, posted by circusboy on September 26, 2006, at 16:37:04
Here is some important info on 5HTP. http://www.lef.org/magazine/hotlines3.html
The article talks about how most 5HTP gets converted to serotonin in the bloodstream OUTSIDE the brain. Then it cannot get past the blood-brain barrier you are left with a ton of 5HT floating around in your blood and what symptoms that can cause.
> I'm a few days into a 5-HTP trial right now. The only thing I can say for sure about it is that when I take it at night, I have (paradoxically?) poorer sleep. I think I'm through with it. ..sigh..
>
> I can't say whether I respond to serotonergic drugs "generally": the only SSRIs I've responded to are Prozac (the weirdest in its class), and very high dose Zoloft (but only with lithium). Desipramine was a revelation...but I couldn't sleep on it.
>
> Anyway. I don't think you'll get any SSRI-like effects from taking SAMe. Let me know if you do.
>
> -cb
>
> P.S. - If you do try SAMe, I'd recommend the Doctor's Best or Jarrow Formulas brand (preferably the latter... and no, I'm not getting a kickback ;)).
>
> > For those of you responding well to SAMe do you respond well to 5HTP/serotonin generally? I've tried Prozac and Paxil and even 5HTP gives me bad akathesia.
>
>
poster:sregan
thread:681487
URL: http://www.dr-bob.org/babble/alter/20060817/msgs/691214.html