Posted by barbaracat on October 13, 2005, at 18:19:58
In reply to Re: Tyrosine vs. Phenylalanine experiences?, posted by Zillah on October 13, 2005, at 11:33:46
Welcome, Zillah. Sorry you're having a poop out to Wellbutrin. I could not tolerate it, although my husband is thriving on it. Our depressions are very different, his lethargic, mine agitated.
I would give macuna a try. All other meds seem to eventually diminish in effect and any other med, such as Selegin or deprenyl, amphetamines, etc. that work on dopamine pathways seem to eventually deplete stores. I've found macuna to be very pleasant with no speediness and gives me an alert yet calm feeling. You can get it at www.herbal-powers.com. Good luck! BarbaraCat
> Please excuse me for barging in... I stumbled across this thread while researching the effects of phenylalanine and tyrosine supplementation on depression.
>
> Your descriptions of your mental/emotional states and responses to medications resonate thoroughly with my own experiences: anhedonia, fatigue, lack of motivation, (very) poor response to SSRIs, problems with attention, disordered sleep, social anxiety.
>
> I've tried Prozac, amitriptyline, Serzone (awful!), Wellbutrin, 5HTP, St. John's Wort, and a myriad of vitamin/mineral supplements. The only thing that has helped me is Wellbutrin.
>
> I've been on Wellbutrin for the past 4 years, but it just isn't working anymore. I feel keyed up and anxious all the time but still apathetic, unfocused, and exhausted. I only recently started researching other substances that work on the dopamine pathway... I'd never heard of macuna.
>
> Are there other medications or supplements you would recommend? I'm currently thinking of talking to my doctor about methylphenidate, selegiline, and/or pramipexole. Any experience with these? What about desipramine or tianeptine?
>
> Thank you,
> Zillah
>
>
poster:barbaracat
thread:559511
URL: http://www.dr-bob.org/babble/alter/20050924/msgs/566555.html