Posted by jasmineneroli on January 20, 2005, at 1:08:07
In reply to Re: A problem with gaba and where the heck's everyone?, posted by Glydin on January 19, 2005, at 16:19:50
Hey all!
I've not been posting recently cuz I've had a return of anxiety, periodically, and been busy with work, plus some sleep problems. AAAAAAAGH!!!I've just come back from my Pdoc and he categorically stated that GABA supplements CANNOT cross the blood-brain barrier, they are a waste of money!
So I think it's the niacinimide that is causing the depression..it did that to me too at 500mg (bedtime dosing). I reduced it to 250mg and feel OK now.Glydin, you and me BOTH!!! Exactly the same result as you.
As you know, I've been trying the tryptophan + niacinimide + magnesium and reduced the clonazepam for the past 2 1/2 months. It's resulted in a recent return of anxiety, and now I have had to go up from my measly .25mg Klon. per day (with an extra .25mg, if stressors increased) to .5mg everyday. This is the opposite of what I was hoping for!
My sleep has been very disturbed too...not what I expected from my humongous dose of Trypt.!! For some reason, the Trypt. worked (sleepwise) when I first increased the dose up towards the 3-3.5 gram range. Then it stopped, and just got worse, not matter what dose I went down to.
I'm very disheartened too :(My Pdoc has no more "drug" solutions, that he thinks will be effective for me, with no side effects..given my history. I felt a bit at a loss today.
One great thing about him though.....he was very interested to hear about Picamilon...had never heard of it before, but feels that it is worth me trying. Believes that in combining GABA with Niacin, it is certainly possible to cross BBB. He wants me to give it a try, and report back to him in two months.
He was theorizing that because a lot of serotonin receptors reside in the GI tract, that much of 5-HTP/tryptophan is absorbed there.
I like the fact that he's open minded and considers/discusses these things. (It's probably because he does a lot of clinical trials).Good grief, I'm babbling here!!! Sorry all.......that's how I get, when the anxiety monster hits.
Hang in everybody.
Jas
poster:jasmineneroli
thread:444287
URL: http://www.dr-bob.org/babble/alter/20050101/msgs/444546.html