Posted by Larry Hoover on November 4, 2004, at 11:37:58
In reply to Re: Bowel toxins,enzyme peptide conversion of aminos? » Larry Hoover, posted by raybakes on November 3, 2004, at 14:37:55
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> > A sulphonase has to be different than a sulphatase, though, as the designated substrate is different.
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> > A sulphoxide has one oxygen double bonded to sulphur. An example is DMSO (dimethyl sulphoxide; methyl- S=O -methyl). An example of a sulphonyl sulphur is MSM, methyl-sulphonyl-methane. It has a two oxygen atoms, double-bonded to sulphur (methyl- O=S=0 -methyl). A sulphonate sulphur has three oxygens, but a single bond to the organic substrate. A sulphate sulphur is sulphur bound to four oxygens, and is bound to the organic substrate by an oxygen bridge.
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> Thanks Larry, you certainly give good value!!I forgot to mention sulfhydryl/sulphydryl (-SH), which is the sulphur analog to the alcohol functional group (-OH). It's the antioxidant centre in glutathione. When the sulphur atom is substituted by selenium, it has more antioxidant capacity. That's where seleno-cysteine and seleno-methionine are so important.
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> I'm fascinated by the sulphur thing because I know how much benefit I personally get to my gut and brain when I take MSM - I get similar effects with sulphate, but I don't get loose stools with MSM.Sulphate is hygroscopic (draws water), just as is magnesium ion. The combination, magnesium sulphate, does a double whammy on the gut, drawing in fluid of hydration to both ions.
MSM is likely absorbed too quickly to lead to hygroscopic events.
> Again in autism they have found that CCK being sulphated helps autistic children, also mucin in the gut needs to be sulphated too.
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> I also did a search for mucin in the brain and came up with this article about glycoproteins being involved in synaptic transmission...what do you think?
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> Ray
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> Glycobiology of the synapseDunno, Ray. My brain says, "enough thinking for now".
Lar
poster:Larry Hoover
thread:407758
URL: http://www.dr-bob.org/babble/alter/20041022/msgs/411662.html