Posted by raybakes on November 2, 2004, at 5:48:30
In reply to i actually have been concerned about my pancreas, posted by joebob on November 1, 2004, at 10:59:11
> as i have been using trazadone for a couple of years now, and used to drink a lot....
>
> hey, suggest away,i'll check out any suggestions on the web and with my naturopath....i don't want to lose any betas, either
>
> i'm waiting on a reply from larry, he may be working now.........think he's in canada
>
> i get my supps at doctors cost and am willing to try whatever seems reasonable
>
> my older brother (2 year) has diabetes
>
> what do you think about r-lipoic acid? and wobenzyme?
>
> still smoke cigs, so any protection for pancreas is important to me, and did have some tenderness in gall bladder region, but cat scan and blood tests showed no concern for the moment
>
> thanks for taking the time to make suggestions
>
> joebob
Does your brother have type 1 or type 2 diabetes? Alpha lipoic acid is a good supplement for blood sugar balance - it helps the insulin receptor work better - I can only tolerate it in small amounts though, in lipothiamine (B1 + lipoic acid) by cardiovascular reseach - it needs to work with B2, B3 as well - I can tolerate large does of naicinamide (1-2 grammes), but only a few mg of B2, before I feel ill.Do you do OK on B6?
Have heard of wobenzyme but not tried it. The one I do well on is serraflazyme by cardiovascular research.
And don't forget fat soluble antioxidants, A, D and E. Alcohol being a solvent, does a good job at dissolving cell membranes. In fact supporting your whole antioxidant system would be a very good idea!!
Here's an abstract about the problems that alcohol leads to in the pancreas - don't read it if you don't want to be spooked! Lipoic acid inhibits NF kappa B, by the way.....and don't forget to try to see someone!
Ray
Mechanisms of alcoholic pancreatitis. Proceedings of a conference. Chicago, Illinois, USA, November 2002.
[No authors listed]
Long-term, heavy alcohol consumption is associated with both acute and chronic pancreatitis. Progression of pancreatitis may lead to multiple comorbidities including maldigestion, diabetes, and pancreatic cancer. Understanding the underlying molecular, biochemical, and cellular mechanisms by which alcohol ingestion leads to the development of pancreatitis may help to develop strategies for the treatment and prevention of the disease. The National Institute on Alcohol Abuse and Alcoholism and the Office of Rare Diseases of National Institutes of Health sponsored a satellite symposium on "Mechanisms of Alcoholic Pancreatitis" at the annual meeting of the American Pancreatic Association, Chicago, IL, November 2002. For this symposium, 8 speakers were invited to address the following issues: (1) epidemiology of alcoholic pancreatitis; (2) pathophysiology of alcoholic pancreatitis; (3) animal models of alcoholic pancreatitis--roles of cholecystokinin (CCK) and viral infections; (4) alcohol and zymogen activation in the pancreatic acinar cell; (5) role of alcohol metabolism in alcoholic pancreatitis; (6) pancreatic stellate cell activation in alcoholic pancreatitis; and (7) genetic predisposition to alcoholic chronic pancreatitis. It was concluded that alcohol abuse is a major contributory factor to the development of both acute and chronic pancreatitis. The injurious effects of ethanol on the pancreas may be mediated through (1) sensitization of acinar cells to CCK-induced premature activation of zymogens; (2) potentiation of the effect of CCK on the activation of transcription factors, nuclear factor kappaB (NF-kappaB) and activating protein-1 (AP-1); (3) generation of toxic metabolites such as acetaldehyde and fatty acid ethyl esters; (4) sensitization of the pancreas to the toxic effects of coxsackievirus B3; and (5) activation of pancreatic stellate cells by acetaldehyde and oxidative stress and subsequent increased production of collagen and other matrix proteins.
poster:raybakes
thread:409337
URL: http://www.dr-bob.org/babble/alter/20041022/msgs/410469.html