Posted by Lamdage22 on January 21, 2023, at 5:26:46
In reply to Re: Is there any evidence that Trazodone curbs OCD?, posted by undopaminergic on January 20, 2023, at 11:05:28
> > > Can anyone interpret the evidence? From what I can tell, it doesnt help much.
> >
> > No, not really. It was the 'med from hell' for me, BUT, I LOVED it's sister drug, nefadozone!! The most UNHARSH antidepressant. Marketed as Serzone in N.America. Don't know about it's effect on OCD, but it has calming effects via 5ht2a blockade.
> >
> > Jay
> >
> >
>
> It seems it is actually an *agonist* at the serotonin 5-HT2C receptor:
> https://pubmed.ncbi.nlm.nih.gov/9618398/
>
> That would translate to an antidopaminergic effect.
>
> -undopaminergicIs that good or bad? There is evidence that Neuroleptics can agitate OCD. I feel they do that with me.
Seroquel 750mg
Zyprexa 17.5mg
Lithium 225mg
Trazodone 75mg
Metformin 2000mg
Orthomolecular
poster:Lamdage22
thread:1121599
URL: http://www.dr-bob.org/babble/20230117/msgs/1121608.html