Posted by Skeletor on November 9, 2020, at 12:46:25
In reply to Re: Currently on low dose Nortriptyline but not sure.., posted by undopaminergic on November 9, 2020, at 12:29:42
> > (I've been thinking about trying Aripiprazole ("Abilify"), in case Nortriptyline won't work)
> >
>
> Probably the only reason aripiprazole sometimes works for depression is that it acts primarily as a dopamine direct agonist at low doses. I strongly recommend you try pramipexole instead, because it acts as an agonist at all doses.
>
> Indeed, pramipexole is the only drug I ever tried that was (temporarily) effective against anhedonia.
>
> -undopaminergic
>Pramipexole sure is interesting, but difficult to come by... most doctors especially in Germany are afraid of full dopamine agonists ^^
Imho Aripiprazole is interesting because it is pro-dopaminergic at low dosages (2 mg) and it exhibits 5HT2-antagonist-properties AND it isn't a strong antihistamine. But yeah, your mileage may vary.
Low dosage of Olanzapine is also interesting, but strong antihistamine... ^^
What is your current regimen?
poster:Skeletor
thread:1112475
URL: http://www.dr-bob.org/babble/20201025/msgs/1112493.html