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Re: Pindolol (a beta-blocker) can alleviate depression

Posted by Hugh on March 4, 2020, at 11:44:04

In reply to Re: Pindolol (a beta-blocker) can alleviate depression, posted by undopaminergic on January 8, 2020, at 2:58:14

It appears that the ideal dosage for treating depression and anxiety and alcoholism is 7.5 mg. Some suggest that if this doesn't help, you should try 10 mg or 12.5 mg. This is still well below the maximum daily dosage of 60 mg.

> > Pindolol is a potent 5ht1a partial agonist and is also useful in the treatment of OCD.
> >
>
> Antagonist actually. It is thought to disinhibit serotonin release by blocking serotonergic autoreceptors located presynaptically. Usually with autoreceptor antagonists, the dose must be kept low, to avoid also blocking postsynaptic receptors.
>
> -undopaminergic
>


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