Posted by SLS on July 9, 2019, at 9:47:37
In reply to Re: IV Ketamine, not nasal spray, posted by SLS on July 6, 2019, at 22:47:58
> Have you heard anything about hydroxynorketamine (HNK)? It is a metabolite of ketamine that can be given orally. It is not supposed to have psychotomimetic or dissociative side effects.
After poking around a little, I am left with the impression that HNK is not as effective as ketamine, even though it raises BDNF levels, increases mTOR signaling, and promotes neuroplasticity in rats. I would still like to see well-controlled human trials. I don't think there are any.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1104648
URL: http://www.dr-bob.org/babble/20190513/msgs/1105215.html