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Re: SSRIs work by numbing emotions? - Myth?

Posted by linkadge on January 15, 2019, at 19:33:05

In reply to Re: SSRIs work by numbing emotions? - Myth?, posted by linkadge on January 15, 2019, at 15:55:03

There are other receptors that are involved too. Activation of 5-ht7, 5-ht6, 5-ht1d, for example, may reduce the dimensions of emotion. Excessive 5-ht1d activation as well, can reduce growth hormone release. It's not just suppression of dopamine. Reduced acetylcholine function can reduce the ability to experience pleasure.

However, I don't agree with the notion that the effect is due to the induction of apathy. Although, for some with emotional over-reactiveness, apathy may be welcome.

Linkadge


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