Posted by SLS on July 1, 2015, at 2:54:24
In reply to Re: Methylene blue for depression?, posted by Christ_empowered on June 30, 2015, at 23:28:09
Luvox (fluvoxamine) monotherapy is an option. Its ability to antagonize sigma-1 receptors is unique among serotonin reuptake inhibitors. Stay away from Zoloft (sertraline). It stimulates sigma-1 receptors, which can make psychotic depression worse.
http://www.annals-general-psychiatry.com/content/9/1/23
http://www.psychiatrictimes.com/articles/understanding-role-sigma-1-receptors-psychotic-depression
I am not aware of there being a general contraindication of taking an SSRI for psychotic depression. Perhaps someone can provide more information regarding this.
Combining a SSRI with a AAP yields better results than using a AAP alone. Of course, Zoloft might be best avoided, despite its use in some studies.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1080121
URL: http://www.dr-bob.org/babble/20150629/msgs/1080132.html