Posted by ed_uk2010 on February 22, 2015, at 15:19:29
In reply to Progress on Parnate - Three-week point » ed_uk2010, posted by Robert_Burton_1621 on February 22, 2015, at 8:17:37
Hi Robert,
Good to hear from you.
>Itching resolved! I only need to take one tablet every second day. No side-effects, either.
Thought it would work :) You can buy other antihistamines but they are not generally as effective.... or they cause more adverse effects.
>I have progressed up to 80mg daily, as of today. I am having no side-effects to speak of.
Good to hear you're tolerating it well. How are you doing in terms of weakness/dizziness and insomnia?
>But there has been no improvement in mood.
I'm sorry to hear that. What were you depression ratings before you started tranyl?
>I did manage to do some low-intensity weight and core training. This was reasurring, though it resulted in no improvement in mood or my "default" state.
It promising you were able to go. I imagine you'd have to go regularly to get the most benefit, both mentally and physically.
>Needless to say, I don't possess the competence to assess the merits of these theories, but they cropped up when I did a few searches seeking information on when parnate can be expected to kick in.
Any thoughts?It's the case with all amine elevating antidepressants (SSRIs, tricyclics, MAOIs etc) that clinical improvement is delayed, even though elevation of monoamines occurs rapidly. All theories appear to revolve around the idea that adaptations must occur in the brain following the increased amine levels, in order for the full AD effect to occur.
I think it's a bit of a waiting game now. I wouln't increase the dose beyond 80mg right now. You can reassess in a few weeks.
Are you still getting headaches?
poster:ed_uk2010
thread:1075968
URL: http://www.dr-bob.org/babble/20150129/msgs/1076987.html