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Re: Zoloft Anxiety at first? » Phillipa

Posted by CamW on February 20, 2013, at 11:18:19

In reply to Re: Zoloft Anxiety at first? » CamW, posted by Phillipa on February 19, 2013, at 20:48:09

> Cam correct me if wrong but I was a psych RN and gave the groups at night. We would discuss how the SSRI's worked. I used to compare it to a spaceship landing on the receptor and the receptor would keep it grounded so to spreak so the receptor would suck up the serotonin. When it was completed it the SSRI would then exit. So now there was a soaked in serotonin synapse of receptor site.
>
> I did always feel that once the receptors got used to being "given" extra serotonin that the receptor didn't make as much on it's own. Hence why poop out might occurr. Am I close? Phillipa

Phillipa - I hadn't thought of it that way. I really had struggled as to why poop-out occurred. I do remember somewhere that serotonin levels were the same before & after poop-out. It could be that the post-synaptic receptors (which I believe also did not change in concentration) become less sensitive to the serotonin.

I'm sorry, I don't have an answer for that. Maybe Scott or Larry Hoover, or other brainiac here might know. I can't seem to recall any good explanation.

- Cam


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URL: http://www.dr-bob.org/babble/20130205/msgs/1038509.html