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Re: Depression is Infectious Inflammation » delna

Posted by SLS on November 14, 2012, at 5:01:41

In reply to Re: Depression is Infectious Inflammation » Phillipa, posted by delna on November 13, 2012, at 20:28:47

> I dropped off my script but I shall have a test to determine baseline values for inflammatory markers first.

What markers are you being tested for?

Ziprasidone and lurasidone are chemically related and share some properties. For me, both drugs produced brain-fog and cognitive impairments at moderate dosages. I found that ziprasidone was helpful for a week or so to reduce my bipolar depression. The major differences between these two drugs in my mind are:

1. Ziprasidone is a weak to moderate potency inhibitor of both norepinephrine and setoroning reuptake (SNRI).

2. Lurasidone is a serotonin 5-HT7 receptor antagonist.

Both drugs are antagonists at dopamine D2 and serotonin 5-HT2a receptors, and are partial agonists at the 5-HT1a receptor.

There is a growing body of evidence that lurasidone is effective for treating depression. Ziprasidone has not garnered as much interest for this indication.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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