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Re: Other folks who can't tolerate MAOIs???

Posted by jono_in_adelaide on September 28, 2012, at 18:28:48

In reply to Re: Other folks who can't tolerate MAOIs??? » ChicagoKat, posted by SLS on September 28, 2012, at 14:04:44

What makes nardil so special is that as well as being an MAO inhibitor, it inhibits the breakdown of GABA, so it can have an almost benzodiazepine like effect on anxiety.

One of its downsides is it is less potent on noradrenalin than some drugs (hence its record of being better in reactive/atypical depression than melancholic/biological depression), hence the addition of nortriptyline - the ultimate combination as it were.

Taking Vitamin B6 along with a daily multi is said to lessen some of Nardils side effects


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