Posted by SLS on July 19, 2011, at 8:20:10
In reply to Re: cannabanoid CB1 agonists are neuroprotective, posted by linkadge on July 18, 2011, at 14:38:43
Hi Linkadge.
> I have used marajuanna twice. Yes, it does have side effects, but to be honest, I found them much less harsh than amitriptyline, and I slep great on it. Nobody here is looking for perfection, just improvement.
Marijuana can ameliorate the pain of depression for some people. This would appear to be true according to what I read on this website. I hope that the study of the CB system can yield treatments that produce less harsh side effects than those currently available. There are so many different systems that can be tweaked, though. It may be that the apparent heterogeneity of presentations of depression will always require a heterogeneity of therapeutic targets to treat them. I guess the holy grail would be to find a mutual single target, if one should exist, from which all cases of depression originate.
Desperate times can lead to a drastic lowering of expectations. I reached this point last September. I was ready to accept but only a partial response to antidepressant treatment, and learn to be happy with that. Then, in November, things began to change for me. I began to improve again. Who knows why it took four months for this to happen. Perhaps this was the time necessary for brain tissues to begin to recover. I would say that the rate of recovery for me is maddeningly slow. It is hard to wait so long for so little return. I am convinced that the chronicity and severity of my case require a great deal of time to recover from. Do we expect too much from antidepressants? Maybe we don't expect enough from our doctors. Because of the treatment modality used in my case, I could never use a psychiatrist who refuses to combine a MAOI with a TCA. It's the only thing that works for me.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.
poster:SLS
thread:991238
URL: http://www.dr-bob.org/babble/20110714/msgs/991391.html