Posted by ed_uk2010 on September 29, 2010, at 14:52:36
In reply to Re: miserable » ed_uk2010, posted by g_g_g_unit on September 28, 2010, at 20:17:14
>I bring my dose back to 75mg immediately. She said that if I still had movement problems in two days, to then reduce the dose to 50mg.
That sounds very reasonable.
>Her reasoning was that I may have titrated too quickly, but since learning that clomipramine is a D2 antagonist, doesn't that mean that the movement problems are not going to be transient?
I believe that it's a very weak D2 antagonist but I doubt that that's responsible for your current symptoms. Muscle twiching and exaggerated reflexes in the legs are typical of potent serotonergic drugs. I think it's a sign that the dose is excessive. Metabolism of clomipramine is extremely variable and dosage requirements vary substantially from person to person. Don't worry about taking any particular 'target dose', just find the dose which reduces your symptoms without causing unacceptable side effects.
poster:ed_uk2010
thread:963674
URL: http://www.dr-bob.org/babble/20100926/msgs/964207.html