Posted by linkadge on May 22, 2010, at 19:50:59
In reply to Re: Imipramine vs Desimpramine, posted by bearfan on May 22, 2010, at 18:20:43
Not necessarily. It depends on the pharmacological activity of the metabolite.
In the case of the TCA's it just so happens that the metabolites show preferential effects on the norepinephrine system.
In the case of venlafaxine, desvenlafaxine is also a poten SNRI. The reasons for the differences (should they occur) between the two is unclear.
poster:linkadge
thread:948247
URL: http://www.dr-bob.org/babble/20100514/msgs/948359.html