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Diphenhydramine HCL and MAOIs - Any Reactions?

Posted by jedi on January 17, 2010, at 0:29:30

Hi Guys,
I did a Google Search on diphenhydramine and MAOI. There were thousands of hits showing the two medications as contraindicated. I have been taking Benadryl off and on for years as a sleep aid with Nardil. Of course you can't mix a decongestant or cough suppressant with the diphenhydramine HCL, but has anybody ever had a reaction from a MAOI and just straight Benadryl?

I guess diphenhydramine HCL can cause hypotension in some people. Since I don't get low blood pressure from Nardil or Benadryl, maybe I am just the exception to the rule.

Anyway, just wondering if anybody has had trouble with mixing the two meds?

Thanks,
Jedi

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URL: http://www.dr-bob.org/babble/20100113/msgs/934010.html