Posted by West on December 25, 2009, at 16:06:36
In reply to Re: Help w/ atypical depression? (my first post here) » West, posted by ace on December 24, 2009, at 17:38:19
Cholinergic rebound. I've heard the term used to describe the phenomenology of feeling better 1-2 days immediately after stopping SSRIs. I don't know whether it is correct.
I have however heard that drugs that increase aCH like piracetam can be depressogenic, which seems to be what you're getting at.
I pulled up a study from google. You can see that CDP-choline, I assume used to mimic aCH, produced a mild increase in DA in the brain, either through promoting synthesis/uptake or inhibiting the release of DA from the neuron. Take that to mean what you will.
www.journalarchive.jst.go.jp/jnlpdf.php?cdjournal=jphs1951&cdvol=31&noissue=1&startpage=47〈=en&from=jnlabstract
poster:West
thread:930645
URL: http://www.dr-bob.org/babble/20091217/msgs/930878.html