Posted by SLS on May 28, 2009, at 22:57:20
In reply to Re: brain reset? » SLS, posted by HyperFocus on May 28, 2009, at 21:44:03
> I once switched to Cymbalta + Risperdal out of frustration, after futilely trying for a long time to recapture a response I had once to amitriptyline + sulpiride. When I switched back to the amitrip/sulpiride I responded. I had tried for a long time with different dosing of amitrip/sulpiride but it seemed totally coming off them and switching to something else was required
>
> Have you considered switching to another regime for a few weeks - say Nardil/nortriptyline/lithium - and then switching back to Parnate/desipramine/Lamictal/Abilify? Maybe this would achieve a sort of reset of your systems and enable you to recapture the response you once had with Parnate/desipramine. Pure uninformed speculation here, but these meds mechanisms we don't really understand. It's not a straightforward dosing application. Why do people not respond again after stopping an effective med the first time, for instance.
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> You've helped so many people here - I wish you all success in your quest for recovery.Thank you.
You are probably not too far off. One of my doctors had a patient who he had cycle between Nardil and Parnate. Others have used the strategy of discontinuing Nardil for 3 months and then be able to recapture the antidepressant response once it was restarted.
I would like to try adding a few more things to what I am currently taking before dumping the Parnate and nortriptyline.
Keep thinking!
Thanks again.
- Scott
poster:SLS
thread:896403
URL: http://www.dr-bob.org/babble/20090524/msgs/898191.html