Re: Sertraline + sigma agonist or antagonist?

Posted by SLS on February 15, 2009, at 11:19:54

In reply to Re: Sertraline + sigma agonist or antagonist?, posted by SLS on February 15, 2009, at 9:16:20

According to Stephen Stahl, sertraline has mild antagonist actions at sigma receptors. Furthermore, sertraline does not potentiate NGF induced neurite growth, indicating that it is not an agonist. On the other hand, fluvoxamine is a fairly potent agonist.

- Scott

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Sertraline + sigma agonist or antagonis? linkadge 2/15/09
Re: Sertraline + sigma agonist or antagonis? » linkadge SLS 2/15/09
Re: Sertraline + sigma agonist or antagonis? » SLS SLS 2/15/09
Re: Sertraline + sigma agonist or antagonis? SLS 2/15/09
Re: Sertraline + sigma agonist or antagonis? linkadge 2/15/09
Re: Sertraline + sigma agonist or antagonist? SLS 2/15/09
Re: Sertraline + sigma agonist or antagonist? SLS 2/15/09
Re: Sertraline + sigma agonist or antagonist? desolationrower 2/16/09
Re: Sertraline + sigma agonist or antagonist? linkadge 2/16/09

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