Posted by X_ander on February 12, 2009, at 21:08:25
In reply to Re: Your vote to treat ANHEDONIA, posted by Jim45 on February 3, 2009, at 15:48:13
Hey Jim, cheers for replying, I'm quite interested in this cos there aren't many options for anhedonia, it really is quite sad...we have to fight for it, I'm glad you have.A few questions on your regimen...(hope you don't mind..)
1) On the breaking and pouring of the capsule.. you use a quarter of a 250mg capsule? That would make your dose around 60mg of PEA...sorry to be pedantic, but I'd like to know: do you go for as close to 100mg as you can or just approximately a quarter of the capsule...?
2) How do you store the rest once the capsule is broken?
3) How do you take the powder once it is out? Just with water or something..?
4) Have you found it absolutely necessary to take selegiline in the quarter/thirds dose as you describe? What happens if you don't?
My reason being that selegiline is an irreversible inhibitor of MAO-B, which allows for the slowing of the PEA breakdown...being irreversible, the effects of selegiline last a lot longer than after the tablet has been metabolised (up to 2 weeks, as you'll know from the warnings on antidepressant labels etc...) so I would have thought it not all that necessary to pace the dose of the selegiline so rigidly throughout the day (kind of like the principle of a drug having a really long half-life....), the effects of the previous doses are still well and truly alive...
my best wishes to you too mate.
poster:X_ander
thread:10100
URL: http://www.dr-bob.org/babble/20090203/msgs/879781.html