Posted by bleauberry on February 3, 2009, at 16:27:57
In reply to Re: Parnate., posted by bulldog2 on February 2, 2009, at 16:49:34
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> > After that mood went downhill rapidly and I developed some nervousness and anxiety that I haven't felt in months. I concluded MAO enzymes were coming back to life and not good for me.
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> Yes I would also conclude that was the result of the maoi enzymes repopulating and not parnate.
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> You say you are med sensitive but what you in fact might be is a slow metabolizer of meds.This med seems to have promise for you.
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> Your challenge and your p-docs challenge is to devise a schedule and doing regemin that will agree with your metabolism. Perhaps a dose every three to four days? Increases in the med by 2.5 milligrams?
>
Very wise observations bulldog2. Thanks for your insight. As you seemed to agree, the timeline at which trouble kicked in was about the expected time that MAO enzymes would have made significant recovery. There is a lab test to check phase I and phase II liver metabolism to see whether someone is a fast metaboliser, slow metaboliser, and which phase of the liver is slower or faster than the other, identifying imbalances that cause overflows of unmetabolised stuff back into the system. That test is expensive and not covered by insurance. Sigh.I like your dosing strategy. My first choice is Marplan. But if it ends up being Parnate, my dosing schedule will likely be something very close to what you suggested.
Thanks for the input!
poster:bleauberry
thread:877625
URL: http://www.dr-bob.org/babble/20090203/msgs/877840.html