Posted by softheprairie on December 26, 2008, at 3:24:17
In reply to Re: Ideas for inattentive-type ADD treatment? » desolationrower, posted by TriedEveryDrug on December 26, 2008, at 0:53:19
> > Have you ever tried a neuroleptic, either with desipramine or a stim?
> >
> > -d/r
>
> That is the one class of drug I have not tried.
>
> I punched a few into epocrates w/ desipramine and they seem to all interact one way or another.
>
> What would you recommend? Risperidone?
>
> thanks
I am on 300 mg desipramine (and the beta blocker nebivolol/Bystolic at 2.5 mg to deal with the overfast heartbeat from the desipramine) and the old-timey neuroleptic perphenazine (currently 4 mg times 1.5 pills/day, but I think I want to go back up to 2 pills/day -had wanted to cut back), and thyroid adjunct (currently 50 mcg Cytomel). I am on these meds for depression; I also have some inattentive ADD, but the meds I'm on haven't helped my inattention (or, conversely, overfocus) as far as I can tell.When I first started desipramine (I gradually increased to 300 mg) I was also on a medium or smallish dose of mixed amphetamine salts, but they didn't mix well with the desipramine, and I made myself pick one or the other, and I picked the desipramine. Part of what got me to make the decision against the stimulant was that I didn't notice it doing much of late for either depression or attention. A side effect I have of the desipramine is more anxiety, as you mentioned. I tried a benzodiazepine to address that (Ativan/lorazepam), but I didn't notice any anxiety relief, just more tiredness, when that's already too present. Sorry if I'm not helpful -- I just got interested in your post since it discusses desipramine, and so few people are on it. But, you may want to look into perphenazine; I like it so far.
poster:softheprairie
thread:870732
URL: http://www.dr-bob.org/babble/20081223/msgs/870837.html