Posted by med_empowered on August 19, 2008, at 12:18:01
In reply to Do Antipsychotics negate/trump stimulants?, posted by qbsbrown on August 19, 2008, at 10:39:18
Combining antipsychotics+stimulants is actually relatively common. Although antipsychotics (especially old, high-potency ones like Haldol) can negate stimulants' effects (so much so that Haldol is used for amphetamine psychosis), the effect really depends on the drug used and the dosages.
For instance: back in the day,there were bunches of low-dose antipsychotic+amphetamine combo pills, such as Eskatrol (prochlorperazine+dexedrine) and ThoraDex (thorazine plus dexedrine). Some docs use Ritalin to overcome sedation from Clozapine or seroquel. Provigil is being used a whole lot with antipsychotics, too.
Sooo...I'd say the combo can be worked out, but its kind of tricky to get the right amount of stimulation (w/o agitation) and the right amount of mood stabilization (w/o sedation or apathy). Plus, if I remember correctly, using amphetamines with antipsychotics might increase the risk of TD over the long haul.Good luck.
poster:med_empowered
thread:847193
URL: http://www.dr-bob.org/babble/20080814/msgs/847210.html