Posted by SLS on May 17, 2008, at 16:24:18
In reply to Re: For SLS - But ALL PLEASE READ! :O), posted by garylee on May 17, 2008, at 16:08:56
> > Dinapsoline is an interesting drug. I guess the only thing I would be concerned with is sudden sedation / sleep attacks similar to what apomorphine is known to produce at low dosages.
> >
> > I am VERY curious how you became interested in D1 agonism.
> Well, (remember this all my armchair pharmacology, which why I ask you! lol) I'm led to believe that Cocaine works as an agonist mainly on the D1 receptor (though I think it's also some sort of SDRI), Cocaine is the only drug that really helps my depression, anxiety, SP, depersonalization/derealization, etc, etc... This all how my hunt for Dopamine meds came about. For a long time I was hunting for Amineptine, the only real SDRI ever made (FDA bans all drugs that make you feel good...f**kers!).I had your personal email addy around 2002, we were speaking for a while, but I think you were a bit worse than you are now and we lost contact. We spoke about Amineptine at great length, amongst other things.
>
> Anyhoo, that's the story behind my Dopamine quest. But going back to the original question have you any knowledge on lab synthesis? Also you knew of Dinapsoline. Is it available anywhere?You know, cocaine is also a norepinephrine AND serotonin reuptake inhibitor. It would be difficult to know how to interpret your improvement reaction to cocaine. What does methylphenidate do for you? Have you ever combined with a serotonin reuptake inhibitor? I'll try to look into D1 receptors. Just know that Mirapex exerts its effects in the limbic system via D3 receptors, those involved with mood and reward.
Sorry, gotta' run now. If I come up with anything, I'll let you know.
> Awaiting your wise reply :O)
Well, I figured you wouldn't want to wait for me to come up with a wise reply, so I gave you this one instead.
Take care.
- Scott
poster:SLS
thread:829689
URL: http://www.dr-bob.org/babble/20080510/msgs/829715.html