Posted by Racer on January 31, 2008, at 2:25:43
In reply to Lexapro - Appetite supression??, posted by cmorhoun on January 29, 2008, at 15:30:59
Actually, that's not unusual with SSRIs -- they often decrease appetite initially, and may cause some weight loss at first. This effect is often lost after about six months -- at which point they may start to cause weight gain. The whole weight thing is largely due to their action on the serotonin receptors in the gut -- that's where about 95% of the serotonin in your body is used.
In general, yes -- the GI upset that some people experience on SSRIs at first does usually go away. Again, that's part of the serotonin activity in your digestive tract -- serotonin mediates gut motility, as well as the signals telling your brain that you're full. Once your body adjusts -- by making the serotonin receptors in question less sensitive to all that serotonin that's tickling them -- the GI troubles usually go away.
I hope that helps.
poster:Racer
thread:809579
URL: http://www.dr-bob.org/babble/20080124/msgs/809872.html