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Re: Any limits to venlafaxine + mirtazapine dosage

Posted by Molybdenum on January 28, 2008, at 19:59:20

In reply to Re: Any limits to venlafaxine + mirtazapine dosage, posted by torachan on January 28, 2008, at 7:38:59

I understand that the soporific effects of Remeron (mirtazapine) are supposed to be more pronounced at the lower end of the dosage spectrum (15mg?) but with me, it has always really helped me to get a good 8 hrs sleep. Trouble is that the effect seems to wear off every few months. When I up the mirtazapine, I get the good sleep again. The Dr said it isn't supposed to work that way. "So sue me", I said..... Although he acknowledges he has no evidence to support such high doses as being "more effective", he also told me that they are relatively no-toxic, so there's little danger of my head exploding, etc. ;)

I take the venlafaxine at 6pm & the mirtazapine at 8pm and I'm generally asleep by 9:30pm.

I used to be quite open to trying different anti-depressants but now that this combo is working & also 'cos the dose is so high, I'm scared that changing now could push me back down & over the edge. :(

I've never had the blurred vision but I did feel a bit sedated on it to start with. Maybe if you stick it out a few more weeks, take it earlier in the evening or even up the dose, the foggyheadedness might go away. ;)


> 225 mg of mirtazapine??? I'm currently on 30 mg of remeron but am considering dropping it after a month or so of usage since it seems to give me this constant foggy headed feeling and blurry vision. Anyone else have this experience? I read somewhere the max dose for rem was 90 mg.
>
> I've also used Effexor in the past at around 150 mg a day, but I've heard doses can go as high as about 400-500 mg's.
>
> I'd say try another drug in the case of remeron if it doesn't help you sleep. Perhaps that high dose is giving you too powerful a norepinephrine kick.
>
>


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URL: http://www.dr-bob.org/babble/20080124/msgs/809436.html