Posted by ny2bk on January 5, 2008, at 22:30:33
In reply to Re: New gaba drug for schizophrenia in pipeline » ny2bk, posted by nellie7 on January 5, 2008, at 12:32:33
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> I have tried supplemental gaba and, contrary to what I have heard, it DOES cross the blood-brain barrier. However, it simply made me tired and numb and was not at all what I was looking for. L-glutamine was better than gaba in that sense (tried that too) , but after several hours it gave me brain zaps, hot flashes and myoclonic jerks, so I didn't take it again.
>Yeah glutamte as a supplement is tricky,unlike gaba there is little debate on whetehr it crosses into the brain,and im sure you know glutamate basicaly works as a moderator,if your low on natural gaba it converts to gaba,and if not it affects the opposite towards the nmda side.
So how to know if the glutmate is gonna take on a nice mellow effect or a agitating one is pretty much guess work which isnt fun at all.
I still have to disagree with ya on gaba though lol,in fact the creator of ghb did so in an attempt to get gaba into the brain as supplemntal gaba did not do it.He would inject supplemental gaba via spinal tap in animals to get it to the brain which created his interest that is was of value,go on from there by adding a carrier,HYDROXIDES,was how he came about ghb which is gaba attatched to a strong based hydroxide.
Look up the name Dr Henri Laborit,he is the one who came across ghb,as well as simply worked on the idea of gaba to the brain for a good part of his career,he was a nobel prize nominee.Gaba does circulate in the body however and can be known to aid sleep this way,this again is just me disagreeing who knows what really happens.
Thanks for the response.
poster:ny2bk
thread:803534
URL: http://www.dr-bob.org/babble/20080105/msgs/804566.html