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Re: going from Zyprexa to Seroquel » your#1fan

Posted by yxibow on December 21, 2007, at 2:18:49

In reply to Re: going from Zyprexa to Seroquel, posted by your#1fan on December 20, 2007, at 23:51:13

> 30mg.....wow. I didnt know they had it that high of a dose.
>
> I take 7.5mg right now for mood stabiliztion, and to calm this brain down. But isnt Zyprexa stonger than Seroquel? on d1 and d2 receptors? anybody read this?
>
> How long does Seroquel last in the system?
>
> fan

Zyprexa is mildly stronger than Seroquel in some ways, it is very strong at D2 for a drug that otherwise is on the weak end of the atypical spectrum, something it shares with its cousin clozapine, though the possible consequences of this bond are not quite the same for some reason.

Seroquel has a half life of 6 hours, Zyprexa I think not much longer -- its the plasma life though that really determines things. After about two weeks or so, sometimes less, you reach a steady state in your blood. That's why its important to not drop it like a turnip.

Now apparently it is possible from what I know to go from some dose of Seroquel to Clozaril inch by inch, so I'd say again, have a doctor skilled try to make the best guestimate and realize that there may be a bumpy road but that perhaps being "unprotected" completely may not be the best thing for some people.

 

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URL: http://www.dr-bob.org/babble/20071213/msgs/801882.html